rs1130214

Polymorphism: rs1130214
rs1130214 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 14q32.32

Factor:
- Symbol: AKT1
- Name: v-akt murine thymoma viral oncogene homolog 1
- Entrez ID: 207
- Ensembl ID: ENSG00000142208

Factors:
  • AKT1 v-akt murine thymoma viral oncogene homolog 1 ( 207 / ENSG00000142208 )


  • Description:

    "AKT1 fails to replicate as a longevity-associated gene "

    OR and P values taken from Table 2: Association analysis of AKT1 variations in long-lived individuals

    Ethnicity: Danish, German
    Age of cases: 92-110
    Finding: Negative

    Statistics
    - Number of cases/controls: 2996 vs 1840 (initial)
    - Odds ratio: 0.97
    - p-value: 0.544 [0.544]
    - Significant: No

    Study Design
    - Classifications: No Age Effect
    - Study type: Candidate Region/Gene
    - Technology: PCR, Illumina GoldenGate Technology

    Reference:
    22929028: AKT1 fails to replicate as a longevity-associated gene in Danish and German nonagenarians and centenarians.

    Choice: Curate_Jimi
    Created: July 1, 2013, 12:55 p.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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