APOE e2/e4

Polymorphism: APOE e2/e4



Location: 19q13.2

Factor:
- Symbol: APOE
- Name: apolipoprotein E
- Entrez ID: 348
- Ensembl ID: ENSG00000130203

Factors:
  • APOE apolipoprotein E ( 348 / ENSG00000130203 )

  • Ethnicity: French
    Age of cases: 100+
    Shorter lived allele: e4
    Longer lived allele: e2

    Statistics
    - Number of cases/controls: 300 vs 160 (initial)
    - Odds ratio: 2.0
    - p-value: 0.001 [0.001]
    - Significant: yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: unknown (old paper)

    Reference:
    8136829: Genetic associations with human longevity at the APOE and ACE loci.

    Choice: Curate_Jimi
    Created: July 1, 2013, 12:45 p.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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