rs2267723

Polymorphism: rs2267723
rs2267723 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 7p14

Factor:
- Symbol: GHRHR
- Name: growth hormone releasing hormone receptor
- Entrez ID: 2692
- Ensembl ID: ENSG00000106128

Factors:
  • GHRHR growth hormone releasing hormone receptor ( 2692 / ENSG00000106128 )

  • Ethnicity: Danish
    Age of cases: 92-93 years old
    Shorter lived allele: G
    Longer lived allele: A
    Finding: Positive

    Statistics
    - Number of cases/controls: 1089 vs 736 (initial) | 1613 vs 1104 (replication)
    - Odds ratio: 0.696
    - p-value: 0.0001 [0.0001]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: Illumina GoldenGate platform

    Reference:
    22406557: Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studies.

    Choice: Curate_Emily
    Created: July 1, 2013, 10:43 a.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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