rs4646994

Polymorphism: rs4646994
rs4646994 ( SNPedia | 23andMe )

Variant Type: Deletion
Location: 17q23.3

Factor:
- Symbol: ACE
- Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
- Entrez ID: 1636
- Ensembl ID: ENSG00000159640

Factors:

ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 ( 1636 / ENSG00000159640 )

Description:

Total population consists of Caucasian Gaucho population and Japanese population, both living in the South of Brasilia. Results are only significant in Gaucho population (GP), not Japanese population (JP)

Ethnicity: Brazilian
Age of cases: 10-104
Shorter lived allele: I
Longer lived allele: D (only for Gaucho population)
Finding: Positive

Statistics
- Number of cases/controls: 834 (initial)
- Odds ratio: 2.25
- Odds ratio type: Longer
- p-value: 0.003 [0.003 (only in Gaucho population)]
- Significant: Yes

Study Design
- Classifications: Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR

Reference:
14528043: Angiotensin I-converting enzyme gene polymorphism in two ethnic groups living in Brazil's southern region: association with age.

Choice: Clean
Created: July 1, 2013, 10:43 a.m.
Updated: Aug. 8, 2014, 1:05 p.m.

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