rs28969505

Polymorphism: rs28969505
rs28969505 ( SNPedia | 23andMe )

Location: 1p35.3

Factor:
- Symbol: YTHDF2
- Name: YTH domain family, member 2
- Entrez ID: 51441
- Ensembl ID: ENSG00000198492


Description:

Short tandem repeat (microsatellite) variation located in the YTHDF2 gene was found to be significantly associated with longevity.

Ethnicity: Italian
Age of cases: age 99–109,years, mean age 101 years; 26 men, 111 women

Statistics
- Number of cases/controls: 137 vs 412 (initial)
- Odds ratio: 2.186
- p-value: 0.023
- Significant: Yes

Study Design
- Classifications: Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR

Reference:
16799135: A polymorphism of the YTHDF2 gene (1p35) located in an Alu-rich genomic domain is associated with human longevity.

Choice: Curate
Created: June 30, 2013, midnight
Updated: Aug. 8, 2014, 1:05 p.m.

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