rs1805415

Polymorphism: rs1805415
rs1805415 ( SNPedia | 23andMe )

Location: 1q41-q42

Factor:
- Symbol: PARP1
- Name: poly (ADP-ribose) polymerase 1
- Entrez ID: 142
- Ensembl ID: ENSG00000143799

Factors:
  • PARP1 poly (ADP-ribose) polymerase 1 ( 142 / ENSG00000143799 )

  • Ethnicity: African American, Caucasian
    Shorter lived allele: G,C
    Longer lived allele: T

    Statistics
    - Number of cases/controls: 479 vs 900 (initial) | 388 vs 364 (replication)
    - Odds ratio: 0.66
    - p-value: 0.001 [0.001]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: TagSNP genotyping, Sequenom MASSarray

    Reference:
    19249341: Inflammation and stress-related candidate genes, plasma interleukin-6 levels, and longevity in older adults.

    Choice: Curate_Johnny
    Created: July 1, 2013, 10:04 a.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

    Edit (Admin) | Delete

    Comment on This Data Unit