APOE e2/e3/e4

Polymorphism: APOE e2/e3/e4



Location: 19q13.2

Factor:
- Symbol: APOE
- Name: apolipoprotein E
- Entrez ID: 348
- Ensembl ID: ENSG00000130203

Factors:
  • APOE apolipoprotein E ( 348 / ENSG00000130203 )


  • Description:

    Candidate gene

    Ethnicity: Finn
    Age of cases: Minimum age 104
    Shorter lived allele: e3, e4
    Longer lived allele: e2

    Statistics
    - Number of cases/controls: 179 (initial)
    - Odds ratio: 4.4
    - p-value: 0.02
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: isoelectric focusing of plasma.

    Reference:
    11213279: Longevity and the epsilon2 allele of apolipoprotein E: the Finnish Centenarians Study.

    Choice: Curate_Johnny
    Created: June 30, 2013, 11:53 p.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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