rs2107538-rs2280789

Polymorphism: rs2107538-rs2280789
rs2107538-rs2280789 ( SNPedia | 23andMe )

Variant Type: Haplotype

Factor:
- Symbol: RANTES
- Name: ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
- Entrez ID: 187011
- Ensembl ID: ENSG00000167283


Description:

Applies to males

Ethnicity: Spaniard
Age of cases: Mean age 89.6
Shorter lived allele: non A-T haplotypes
Longer lived allele: A-T
Finding: Positive

Statistics
- Number of cases/controls: 104 vs 110 (initial)
- Odds ratio: 4.9
- p-value: 0.03 [0.03]
- Significant: Yes

Study Design
- Classifications: Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: Must purchase article to view

Reference:
22265023: Distribution of functional polymorphic variants of inflammation-related genes RANTES and CCR5 in long-lived individuals.

Choice: Curate
Created: Aug. 11, 2013, 3:30 p.m.
Updated: Aug. 8, 2014, 1:06 p.m.

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