rs2542052

Polymorphism: rs2542052
rs2542052 ( SNPedia | 23andMe )

Location: 11q23.3

Factor:
- Symbol: APOC3
- Name: apolipoprotein C-III
- Entrez ID: 345
- Ensembl ID: ENSG00000110245

Factors:

APOC3 apolipoprotein C-III ( 345 / ENSG00000110245 )

Description:

In a prospectively studied cohort, a significant survival advantage is demonstrated in those with the favorable -641C homozygousity (p < 0.0001) [16602826].

Ethnicity: Ashkenazi Jewish
Shorter lived allele: A

Statistics
- Number of cases/controls: 213 old vs 216 offspring vs 258 controls (initial)
- p-value: 0.0001
- Significant: Yes

Study Design
- Classifications: Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR

Reference:
16602826: Lipoprotein genotype and conserved pathway for exceptional longevity in humans.

Choice: Curate
Created: July 2, 2013, 1:13 p.m.
Updated: Aug. 8, 2014, 1:06 p.m.

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