rs429358, rs7412

Polymorphism: rs429358, rs7412
rs429358, ( SNPedia | 23andMe )
rs7412 ( SNPedia | 23andMe )

Location: 19q13.2

Factor:
- Symbol: APOE
- Name: apolipoprotein E
- Entrez ID: 348
- Ensembl ID: ENSG00000130203

Factors:

APOE apolipoprotein E ( 348 / ENSG00000130203 )

Ethnicity: American, Caucasian
Age of cases: Mean age 100,8
Shorter lived allele: e4
Longer lived allele: e2

Statistics
- Number of cases/controls: 318 vs 350 (initial) | 376 vs 506 (replication)
- p-value: 0.0005 [<0.0005]
- Significant: Yes

Study Design
- Classifications: Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR

Reference:
18034366: Lack of replication of genetic associations with human longevity.

Choice: Curate
Created: July 2, 2013, 2:54 a.m.
Updated: Aug. 9, 2014, 11:42 p.m.

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