55 (L/M)

Polymorphism: 55 (L/M)



Location: 7q21.3

Factor:
- Symbol: PON1
- Name: paraoxonase 1
- Entrez ID: 5444
- Ensembl ID: ENSG00000005421

Factors:

PON1 paraoxonase 1 ( 5444 / ENSG00000005421 )

Description:

LL,LM and MM genotypes of PON 55 polymorphisms showed similar frequencies in Italy (39.9, 47.0, 13.1%) and Ireland (39.5, 48.6, 11.9%) with no age or sex-related differences. Detailed OR information is as follows: 0.94 (0.8-1.1)

Ethnicity: Irish, Italian
Age of cases: Italian 100.8 years, Irish 89.8 years

Statistics
- Number of cases/controls: 308 vs 579 Italian, 296 vs 296 Irish (initial)
- Odds ratio: 0.94
- p-value: 0.44
- Significant: No

Study Design
- Study type: Candidate Region/Gene
- Technology: PCR-RFLP

Reference:
15050299: Paraoxonase polymorphisms PON1 192 and 55 and longevity in Italian centenarians and Irish nonagenarians. A pooled analysis.

Choice: Curate
Created: June 30, 2013, midnight
Updated: Aug. 8, 2014, 1:05 p.m.

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