rs2769255
Polymorphism: rs2769255
rs2769255
(
SNPedia |
23andMe
)
Location: 1p34
Factor:
- Symbol: KCNQ4 (upstream)
- Name: potassium voltage-gated channel, KQT-like subfamily, member 4
- Entrez ID: 9132
- Ensembl ID: ENSG00000117013
Factors:
KCNQ4 (upstream)
potassium voltage-gated channel, KQT-like subfamily, member 4
(
9132
/
ENSG00000117013
)
Description:
HERE IS USED NOT Odds RATIO TO BECOME CENTENARIAN BUT Hazard RATIO (to die younger or to have CVD or any other negative event during the study). Alleles are shown as authors mention them (in general dbSNP
s and author`s designations are similar)
Ethnicity:
American
Shorter lived allele: T
Statistics
- Number of cases/controls: 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) (initial)
| Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project (replication)
- Odds ratio: 1.079
- p-value:
5.17e-06
[0.00000517]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Genome-Wide Association Study
- Technology: Version 3 Illumina Infinium II HumanHap550 SNP chip array, Illumina 370CNV, Affymetrix GeneChip SNP Array 6.0, Illumina 370CNV, Illumina 550K, Illumina 550K, Illumina Human1M-Duo, Affymetrix SNP Array 6.0, respectively.
Reference:
21782286: A genome-wide association study of aging.
Choice: Curate
Created: July 2, 2013, 2:54 a.m.
Updated: Aug. 8, 2014, 1:05 p.m.
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