HUMTHO1 (STR)

Polymorphism: HUMTHO1 (STR)



Location: 18p11.32

Factor:
- Symbol: THO
- Name: THO complex 1
- Entrez ID: 9984
- Ensembl ID: ENSG00000079134

Factors:
  • THO THO complex 1 ( 9984 / ENSG00000079134 )


  • Description:

    This association may preferentially affect genotype frequencies in male centenarians.

    Ethnicity: Italian
    Age of cases: >100
    Shorter lived allele: 9-10 (long alleles, homozygous genotype)
    Finding: Positive

    Statistics
    - Number of cases/controls: 196 (143 f, 53 m) vs 358 (296 f; 64 m) (initial)
    - p-value: 0.05 [<0.05]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: PCR

    Reference:
    9887369: Gene/longevity association studies at four autosomal loci (REN, THO, PARP, SOD2).

    Choice: Curate
    Created: July 2, 2013, 2:54 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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