rs1801133

Polymorphism: rs1801133
rs1801133 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 1p36.3

Factor:
- Symbol: MTHFR
- Name: methylenetetrahydrofolate reductase (NAD(P)H)
- Entrez ID: 4524
- Ensembl ID: ENSG00000177000

Factors:
  • MTHFR methylenetetrahydrofolate reductase (NAD(P)H) ( 4524 / ENSG00000177000 )

  • Ethnicity: Ashkenazi Jewish
    Age of cases: Mean age 75
    Longer lived allele: C
    Finding: Positive

    Statistics
    - Number of cases/controls: (150 m, 74 f) vs (121 m, 320 f) (initial)
    - p-value: 0.029 [0.029 (females)]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: PCR

    Reference:
    15621215: Candidate genes associated with ageing and life expectancy in the Jerusalem longitudinal study.

    Choice: Curate
    Created: July 2, 2013, 2:54 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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