rs1516507

Polymorphism: rs1516507
rs1516507 ( SNPedia | 23andMe )

Location: 10q22.3

Factor:
- Symbol: KCNMA1
- Name: potassium large conductance calcium-activated channel, subfamily M, alpha member 1
- Entrez ID: 3778
- Ensembl ID: ENSG00000156113

Factors:

KCNMA1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 ( 3778 / ENSG00000156113 )

Ethnicity: Dutch
Age of cases: Mean age 94
Longer lived allele: G

Statistics
- Number of cases/controls: 403 vs 1670 (initial) | 3746 vs 5912 (replication)
- Odds ratio: 1.36
- p-value: 9.67e-05 [9.67x10^-5]
- Significant: Yes

Study Design
- Classifications: Longevity-Associated
- Study type: Genome-Wide Association Study
- Technology: Illumina Infinium HD Human660W-Quad BeadChips; Illumina Infinium II HumanHap550-Duo BeadChips

Reference:
21418511: Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.

Choice: Curate
Created: July 2, 2013, 2:54 a.m.
Updated: Aug. 8, 2014, 1:05 p.m.

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