rs10194564

Polymorphism: rs10194564
rs10194564 ( SNPedia | 23andMe )

Location: 2q21.2

Factor:
- Symbol: Intergenic (upstream of LRP1B)
- Name: low density lipoprotein receptor-related protein 1B
- Entrez ID: 53353
- Ensembl ID: ENSG00000168702

Factors:

Intergenic (upstream of LRP1B) low density lipoprotein receptor-related protein 1B ( 53353 / ENSG00000168702 )

Ethnicity: Dutch
Age of cases: Mean age 94
Longer lived allele: A

Statistics
- Number of cases/controls: 403 vs 1670 (initial) | 3746 vs 5912 (replication)
- Odds ratio: 1.55
- p-value: 8.88e-05 [8.88x10^-5]
- Significant: Yes

Study Design
- Classifications: Longevity-Associated
- Study type: Genome-Wide Association Study
- Technology: Illumina Infinium HD Human660W-Quad BeadChips; Illumina Infinium II HumanHap550-Duo BeadChips

Reference:
21418511: Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.

Choice: Curate
Created: July 2, 2013, 2:54 a.m.
Updated: Aug. 8, 2014, 1:05 p.m.

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