rs10502005

Polymorphism: rs10502005
rs10502005 ( SNPedia | 23andMe )

Location: 11q22.3

Factor:
- Symbol: MMP20
- Name: matrix metallopeptidase 20
- Entrez ID: 9313
- Ensembl ID: ENSG00000137674

Factors:

MMP20 matrix metallopeptidase 20 ( 9313 / ENSG00000137674 )

Ethnicity: Dutch
Age of cases: Mean age 94
Longer lived allele: A

Statistics
- Number of cases/controls: 403 vs 1670 (initial) | 3746 vs 5912 (replication)
- Odds ratio: 1.48
- p-value: 2.42e-05 [2.42x10^-5]
- Significant: Yes

Study Design
- Classifications: Longevity-Associated
- Study type: Genome-Wide Association Study
- Technology: Illumina Infinium HD Human660W-Quad BeadChips; Illumina Infinium II HumanHap550-Duo BeadChips

Reference:
21418511: Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.

Choice: Curate
Created: July 2, 2013, 2:54 a.m.
Updated: Aug. 8, 2014, 1:05 p.m.

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