rs2111699

Polymorphism: rs2111699
rs2111699 ( SNPedia | 23andMe )

Location: 14q24.3

Factor:
- Symbol: GSTZ1
- Name: glutathione transferase zeta 1
- Entrez ID: 2954
- Ensembl ID: ENSG00000100577

Factors:

GSTZ1 glutathione transferase zeta 1 ( 2954 / ENSG00000100577 )

Ethnicity: Calabrian
Age of cases: 90+, median 92
Shorter lived allele: A

Statistics
- Number of cases/controls: 288 vs 554 (initial)
- p-value: 0.0014 [0.0014]
- Significant: Yes

Study Design
- Classifications: Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: allele-specific PCR-based KASPar SNP genotyping system (KBiosciences, Hoddesdon, UK) (Cuppen

Reference:
22576335: MAP3K7 and GSTZ1 are associated with human longevity: a two-stage case-control study using a multilocus genotyping.

Choice: Curate
Created: July 2, 2013, 2:48 a.m.
Updated: Aug. 8, 2014, 1:06 p.m.

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