rs282070

Polymorphism: rs282070
rs282070 ( SNPedia | 23andMe )

Location: 6q15

Factor:
- Symbol: MAP3K7
- Name: mitogen-activated protein kinase kinase kinase 7
- Entrez ID: 6885
- Ensembl ID: ENSG00000135341

Factors:

MAP3K7 mitogen-activated protein kinase kinase kinase 7 ( 6885 / ENSG00000135341 )

Description:

Study consisted of two stages (stage 2 only was recorded here)

Ethnicity: Calabrian
Age of cases: 90+, median 92
Shorter lived allele: G

Statistics
- Number of cases/controls: 288 vs 554 (initial)
- p-value: 0.0011 [0.0011]
- Significant: Yes

Study Design
- Classifications: Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: allele-specific PCR-based KASPar SNP genotyping system (KBiosciences, Hoddesdon, UK) (Cuppen

Reference:
22576335: MAP3K7 and GSTZ1 are associated with human longevity: a two-stage case-control study using a multilocus genotyping.

Choice: Curate
Created: July 2, 2013, 2:48 a.m.
Updated: Aug. 8, 2014, 1:06 p.m.

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