rs13320360

Polymorphism: rs13320360
rs13320360 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 3p21.3

Factor:
- Symbol: MLH1
- Name: mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- Entrez ID: 4292
- Ensembl ID: ENSG00000076242

Factors:

MLH1 mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) ( 4292 / ENSG00000076242 )

Description:

Sig. in males

Ethnicity: Danish
Age of cases: 92.2–93.8 (mean age 93.2) w/ 11.4 years follow-up
Shorter lived allele: A
Finding: Positive

Statistics
- Number of cases/controls: 1089 (see notes - follow-up study) (initial) | 563 (see notes - follow-up study) (replication)
- Odds ratio: 3.132
- p-value: 0.0036 [0.0036]
- Significant: Yes

Study Design
- Classifications: Longevity-Associated
- Study type: Candidate Region/Gene

Reference:
22406557: Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studies.

Choice: Curate
Created: July 2, 2013, 2:48 a.m.
Updated: Aug. 8, 2014, 1:06 p.m.

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