rs770087

Polymorphism: rs770087
rs770087 ( SNPedia | 23andMe )

Location: 12q22-q23

Factor:
- Symbol: DUSP6
- Name: dual specificity phosphatase 6
- Entrez ID: 1848
- Ensembl ID: ENSG00000139318

Factors:

DUSP6 dual specificity phosphatase 6 ( 1848 / ENSG00000139318 )

Ethnicity: German
Age of cases: 100 to 110, mean age = 101.3
Shorter lived allele: C

Statistics
- Number of cases/controls: 386 vs 410 (initial) | 541 vs 469 (replication)
- Odds ratio: 1.53
- p-value: 0.002 [0.002]
- Significant: Yes

Study Design
- Classifications: Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: SNPlexTM Genotyping System (Applied Biosystems)

Reference:
20800603: Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.

Choice: Curate
Created: July 2, 2013, 2:48 a.m.
Updated: Aug. 8, 2014, 1:06 p.m.

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