Fruit flies with additional expression of the elongation factor EF-1 alpha live longer.

Authors: Shepherd JC; Walldorf U; Hug P; Gehring WJ
Year: 1989
Journal: Proceedings of the National Academy of Sciences of the United States of America
Abstract: In Drosophila melanogaster, the decrease in protein synthesis that accompanies aging is preceded by a decrease in elongation factor EF-1 alpha protein and mRNA. Here we show that Drosophila transformed with a P-element vector containing an EF-1 alpha gene under control of hsp70 regulatory sequences have a longer life-span than control flies.
Reference

Integration:

Created on Nov. 5, 2012, 6:23 p.m.
Not linked
Integrated: False

No notes
Species: Fruit fly

Experiments: 0
Interventions:

Ef1alpha48D overexpression

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