| 531 | Table 3 Parameters of life span in female SHR mice treated and not treated with metformin | ✘ | — | — | Mutation | — | — | — | 535.0 | 570.0 | 898.0 | 50 |
| 530 | Table 3 Parameters of life span in female SHR mice treated and not treated with metformin | ✔ | — | — | Mutation | — | — | — | 388.0 | 297.0 | 814.0 | 50 |
| 529 | Table 4 Effect of metformin on parameters of life span in female HER-2/neu mice | ✘ | — | — | Mutation | — | — | — | 285.0 | — | 340.0 | 32 |
| 528 | Table 4 Effect of metformin on parameters of life span in female HER-2/neu mice | ✔ | — | — | Mutation | — | — | — | 264.0 | — | 311.0 | 34 |
| 327 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✘ | w1118 | da-GAL4/UAS-dTORFRB | — | — | — | — | 72.0 | — | 89.0 | 112 |
| 324 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✘ | w1118 | da-GAL4/UAS-dTsc2 | — | — | — | — | 69.0 | — | 88.0 | 134 |
| 525 | Fig. 3. Animal survival and growth | ✘ | Wistar | — | Mutation | — | — | — | 62.0 | 42.0 | 66.0 | 6 |
| 322 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✔ | w1118 | +/da-GAL4 | — | — | — | — | 58.0 | — | 78.0 | 133 |
| 323 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✘ | w1118 | +/UAS-dTsc2 | — | — | — | — | 56.0 | — | 74.0 | 126 |
| 326 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✘ | w1118 | +UAS-dTORFRB | — | — | — | — | 55.0 | — | 71.0 | 128 |
| 325 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✔ | w1118 | +/da-GAL4 | — | — | — | — | 48.0 | — | 79.0 | 133 |
| 50 | TABLE 2 Adult life span profiles A. At 25° | ✔ | — | Canton-S | — | — | 25.0 | — | 46.85 | — | 68.0 | 264 |
| 84 | Figure 2: Overexpression of CG6783 or CG13890 throughout the whole body extends lifespan, which is associated with diet restriction. | ✘ | white1118 | EPCG6783/+ | — | — | — | — | 46.0 | — | 70.0 | — |
| 85 | Figure 2: Overexpression of CG6783 or CG13890 throughout the whole body extends lifespan, which is associated with diet restriction. | ✘ | white1118 | da>EPCG6783 | — | — | — | — | 46.0 | 58.0 | 72.0 | — |
| 138 | Figure 6: Deletion of AFG3 reduces cytoplasmic translation and extends life span by a Sir2-independent, Gcn4-dependent mechanism | ✘ | — | sir2;fob1;afg3 | — | — | 30.0 | — | 46.0 | 44.0 | 78.0 | 20 |
| 140 | Figure 6: Deletion of AFG3 reduces cytoplasmic translation and extends life span by a Sir2-independent, Gcn4-dependent mechanism | ✘ | — | sir2;fob1;afg3 | Dietary Restriction | — | 30.0 | — | 45.3 | 48.0 | 67.0 | 20 |
| 210 | Figure 4 | Calorie restriction extends lifespan by regulating vacuolar acidity. | ✘ | S288c | WT | Dietary Restriction | — | — | — | 45.0 | 45.0 | 75.0 | 31 |
| 214 | Figure 4 | Calorie restriction extends lifespan by regulating vacuolar acidity. | ✘ | S288c | WT | Dietary Restriction | — | — | — | 44.0 | 43.5 | 76.0 | 40 |
| 139 | Figure 6: Deletion of AFG3 reduces cytoplasmic translation and extends life span by a Sir2-independent, Gcn4-dependent mechanism | ✘ | — | sir2;fob1 | Dietary Restriction | — | 30.0 | — | 42.9 | 50.0 | 64.0 | 20 |
| 215 | Figure 4 | Calorie restriction extends lifespan by regulating vacuolar acidity. | ✘ | S288c | VMA1(OE) | — | — | — | — | 42.0 | 43.0 | 75.0 | 36 |
| 63 | TABLE 2 Adult life span profiles A. At 25° | ✘ | — | atg8aep362 | — | — | 25.0 | — | 41.9 | — | 66.0 | 150 |
| 524 | Fig. 3. Animal survival and growth | ✘ | Wistar | — | Mutation | — | — | — | 41.0 | 26.0 | 58.0 | 6 |
| 216 | Figure 4 | Calorie restriction extends lifespan by regulating vacuolar acidity. | ✘ | S288c | VMA1(OE) | Dietary Restriction | — | — | — | 40.0 | 40.0 | 64.0 | 38 |
| 197 | Figure 2 | Vacuolar acidity is reduced in ageing cells and regulates mitochondrial function and lifespan. | ✘ | S288c | VMA1(OE) | — | — | — | — | 39.0 | 39.0 | 80.0 | 56 |
| 132 | Figure 6: Deletion of AFG3 reduces cytoplasmic translation and extends life span by a Sir2-independent, Gcn4-dependent mechanism | ✘ | — | afg3;fob1 | — | — | 30.0 | — | 38.3 | 40.0 | 60.0 | 40 |
