Denigma

Interventions

  • Species: + -
    Fruit fly « 
  • Manipulation: + -
    Gain‑of‑Function «  Loss‑of‑Function « 
    • name effect species mean median maximum
    pex1 mutation Mutation of the promoter region of pex1(S4868), results in lower expression levels and increases lifespan in males and females by 16% and 13%, respectively. pex1 mutation increases mean and maximum lifespan and males/females by 27-23/14-19% and 0-15%, respectively [22509016]. Fly +14 to +27 — 0 to +15
    • 1 intervention
    Interventions are an extension of GenAge and GenDR.