elo-1 RNAi | elo-1 RNAi in the adulthood extends lifespan by 11% [21386131]. | Worm | — | +11 | — |
elo-2 RNAi | elo-1 RNAi in the adulthood extends lifespan by 8% [21386131]. | Worm | — | +8 | — |
fat-4 RNAi | fat-4 RNAi in the adulthood extends lifespan by 25% [21386131]. | Worm | — | 25 | — |
fat-3 RNAi | fat-3 RNAi in the adulthood extends lifespan by 10-15% [19301819]. | Worm | — | 10-15 | — |
aak-2 mutation | aak-2(ok524) knockout mutants have a 12% and 18% shorter mean and maximum lifespan, respectively as well as faster age-dependent accumulation of a lipofuscin-like fluorescent pigment in the intestine [15574588]. aak-2 mutation suppresses lifespan extension and delay of the decline in locomotor activity resulting from sDR [17900900]. aak-2 mutation cancels out the lifespan extension effect of sDR and PD, regardless of the concentration of bacteria or peptones. bDR significantly extends lifespan of aak-2 mutants, but to lesser extent than that of wild-type. eat-2 mutation extends the lifespan of aak-2 mutants to the same extent than that of wild-type. Resveratrol does not increase lifespan of aak-2 mutants [19239417]. daf-2(m577);aak-2(ok524) double mutant has a lifespan that is indistinguishable from those of aak-2(ok524) single mutant [15574588]. | Worm | -12 | — | -18 |
apr-1 RNAi | apr-1 RNAi in the adulthood extends the lifespan [99999999]. | Worm | — | — | — |
snap-29 RNAi | RNAi against snap-29 starting in the adulthood decreases mean and maximum lifespan by 49 and 72%, respectively [23144747]. | Worm | -48.6 | — | -72.0 |
F35G12.4 RNAi | RNAi against F35G12.4 starting in the adulthood decreases the lifespan [New longevity regulators]. | Worm | — | — | — |
cdtl-7 RNAi | RNAi against cdtl-7 starting in the adulthood decreases mean and maximum lifespan by 22 and 25%, respectively [23144747]. | Worm | -22.2 | — | -25.0 |
vha-2 RNAi | RNAi against vha-2 starting in the adulthood decreases the lifespan [New longevity regulators]. | Worm | — | — | — |
mtch-1 RNAi | RNA interference against mtch-1 post-development extends mean lifespan by 21% [17411345]. mtch-1 RNAi in the adulthood extends the lifespan by 2.4 [New longevity regulators]. | Worm | +2.4 to 21 | — | — |
cdc-25.3 RNAi | RNA interference against cdc-25.3 extends lifespan [16741121]. cdc-25.3 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
gei-9 RNAi | RNA interference against gei-9 increases mean lifespan by 57% [17608836]. | Worm | — | — | — |
rpn-11 RNAi | rpn-11 RNAi in the adulthood decreases mean and maximum lifespan by 19 and 25%, respectively [23144747]. | Worm | -19.3 | — | -25.0 |
rol-3 RNAi | rol-3 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
rab-5 RNAi | rab-5 RNAi in the adulthood reduces the lifespan by 38.0% [New longevity regulators]. | Worm | -38.0 | — | — |
pkc-3 RNAi | pkc-3 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
mex-5 RNAi | mex-5 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
his-69 RNAi | his-69 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
his-55 RNAi | his-55 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
grs-1 RNAi | grs-1 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
F54D5.11 RNAi | F54D5.11 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
F38E11.5 RNAi | F38E11.5 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
rpn-7 RNAi | rpn-7 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |
par-6 RNAi | par-6 RNAi in the adulthood extends the lifespan [New longevity regulators]. | Worm | — | — | — |