Interventions

  • name effect species mean median maximum
    git3 constitutive activative mutation Constitutive activation of the G-alpha subunit acting downstream of Git3 accelerates aging and inhibits the effect of DR [19266076].
    gpa2 constitutive active mutation Constitutive active mutation of gpa2 (alias git8) decreases chronological lifespan under AL (2% glucose) and almost completely cancels out the lifespan extending effect of DR (0.2% glucose) [19266076].
    atf1 overexpression Overexpressing atf1 is not sufficient to promote chronological lifespan extension in cells lacking sty1 [20075862].
    wis1 constitutive active mutation Constitutive active mutation of wis1 extends chronological lifespan and there is no further beneficial effect of DR [20075862].
    • 4 interventions
    Interventions are an extension of GenAge and GenDR.