| cep-1 RNAi | RNA interference of cep-1 increases mean lifespan up to 18% which is dependent upon functional daf-16 [17895432]. | Worm | +18 | — | — |
| cel-1 RNAi | RNA interference of cel-1 decreases median lifespan 76% in daf-2 mutants, 15% in daf-2/daf-16 double mutants, and 59% wild-type animals [18006689]. | Worm | — | -76 | — |
| ceh-18 RNAi | RNA interference of ceh-18 extends lifespan [15998808]. | Worm | — | — | — |
| cdk-7 RNAi | RNA interference of cdk-7 decreases median lifespan by 18% in a daf-2 background and 19% in daf-2/daf-16 double mutants [18006689]. | Worm | — | -18 | — |
| cdc-25.3 knockout | cdc-25.3 knockout mutants also display increased thermotolerance and a 40% lifespan extension [16741121]. | Worm | +40 | — | — |
| cdc-25.1 RNAi | RNA interference of cdc-25.1 results in increased thermotolerance and extended lifespan [16741121]. cdc-25.1 RNAi extends mean and maximum lifespan by 10 and 13%, respectively [21129974].
Lifespan extension by cdc-25.1 RNAi is cancelled out by mir-71 mutation [21129974]. | Worm | +10.0 | — | +12.5 |
| cct-6 RNAi | RNA interference cct-6 in adulthood results in a 20% increase in mean lifespan [17411345]. | Worm | +20 | — | — |
| cct-4 RNAi | RNA interference of cct-4 in adulthood results in a 28% increase in mean lifespan [17411345]. | Worm | +28 | — | — |
| ccr-4 RNAi | RNA interference of ccr-4 decreases median lifespan by 33% in wild type animals, 37% in a daf-2 background and 44% in daf-2/daf-16 double mutants [18006689]. | Worm | -33 | — | — |
| cco-2 RNAi | RNA interference of cco-2 results in a 53-57% increase in mean lifespan [16103914]. | Worm | +45 to +57 | — | — |
| calu-1 RNAi | RNA interference of calu-1 decreases median lifespan by 23% in a daf-2 background and 15% in daf-2/daf-16 double mutants [18006689]. | Worm | — | -23 | — |
| C56G2.1 RNAi | RNA interference of C56G2.1 in adulthood results in a 20% increase in mean lifespan [17411345]. | Worm | +20 | — | — |
| C47E12.2 RNAi | RNA interference of C47E12.2 increases mean lifespan by 36% [17608836]. | Worm | +36 | — | — |
| C46G7.2 RNAi | RNA interference of C46G7.2 increases mean lifespan by 44% [17608836]. | Worm | +44 | — | — |
| C42C1.3 RNAi | RNA interference of C42C1.3 increases mean lifespan by 60% [17608836]. | Worm | +60 | — | — |
| trim-9 RNAi | RNA interference of trim-9 extends lifespan [15998808]. | Worm | — | — | — |
| C36H8.1 RNAi | RNA interference of C36H8.1 extends lifespan [15998808]. | Worm | — | — | — |
| C35A11.3 RNAi | RNA interference of C35A11.3 extends lifespan [15998808]. | Worm | — | — | — |
| C33H5.18 RNAi | RNA interference of C33H5.18 extends lifespan [15998808]. | Worm | — | — | — |
| C33A12.1 RNAi | RNA interference of C33A12.1 increase mean lifespan by 40% [17608836]. | Worm | +40 | — | — |
| C32H11.5 RNAi | RNA interference of C32H11.5 extends lifespan [15998808]. | Worm | — | — | — |
| C32H11.1 RNAi | RNA interference of C32H11.1 extends lifespan [12845331]. | Worm | — | — | — |
| C29F9.2 RNAi | RNA interference of C29F9.2 decreases median lifespan by 12% in wild type animals and 36% in daf-2 mutants [18006689]. | Worm | — | -12 | — |
| C29F9.1 RNAi | RNA interference of C29F9.1 decreases median lifespan by 35% in daf-2 mutants [18006689]. | Worm | — | — | — |
| vps-22 RNAi | RNA interference of vps-22 decreases median lifespan by 43% in wild type animals, 33% in a daf-2 background and 9% in daf-2/daf-16 double mutants [18006689]. | Worm | — | -43 | — |
GenAge
GenDR
