Denigma

CHL1 deletion

Species: Budding yeast (Taxid: 4932)
Factor: CHL1
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion
Effect:

CHL1 deletion mutant exhibits a shortened mean and maximum lifespan by 36 and 29%, respectively, as well as hypersensitivity to heat stress. CHL1 may modulate transcriptional silencing in the presence of Sir proteins [16182251].

Mean: -36
Maximum: -29

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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