Denigma

UTH1 deletion

Species: Budding yeast (Taxid: 4932)
Factor: UTH1
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion
Effect:

Mutation in UTH1 increases replicative lifespan by approximately 15% [7859289].

UTH1 mutant has enhanced stress resistance to cold stress [7859289], heat shock [10870102], starvation [7859289], hydrogen peroxide, but is sensitive to paraquat and oxygen [9799359].

Mean: +15

References:
  • 7859289: Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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