Top3b knockout

Species: House mouse (Taxid: 10090)
Factor: Top3b
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion
Effect:

Homozygous disruption of Top3b results in a normal development but a shorter lifespan (by approximately 70%) accompanied by lesions in multiple organs in C57BL/6 [11331780].

Mean: -70

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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