Inhibition of sgk-1 activity by RNAi results in an lifespan extension by approximately 63% which is suppressed by mutation of daf-16 [15068796].
Inactivation of sgk-1 by RNAi results in animals that have severe a egg-laying defect, extended generation time, increased stress resistance, i.e. pleitropic phenotypes similar to mutants in daf-2, age-1, and pdk-1 [15068796].
Mean: +63
GenAge
GenDR
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