Denigma

osm-5 mutation

Species: Nematode (Taxid: 6239)
Factor: osm-5
Manipulation: Loss-of-Function, Knockout, Mutation
Effect:

Loss-of-function mutation in osm-5 can increase lifespan by 100-150% [10617200].

osm-5 mutants are dauer-defective (suppressed by daf-2) [1732156] and chemotaxis defective [8348618], as well as day filling defective [Starich et al. 1995].

Mean: +100 to +150

References:
  • 10617200: Regulation of lifespan by sensory perception in Caenorhabditis elegans.
  • 1732156: Genetic analysis of chemosensory control of dauer formation in Caenorhabditis elegans.
  • 8348618: Odorant-selective genes and neurons mediate olfaction in C. elegans.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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