osm-1 mutation

Species: Nematode (Taxid: 6239)
Factor: osm-1
Manipulation: Loss-of-Function, Knockout, Mutation
Effect:

Loss-of-function mutation in osm-1 increases lifespan by up to 40% [10617200].

osm-1 mutants are defective in chemotaxis, dye filling and daufer formation, have short axonemes and ectopicassembly of ciliary structures and microtubules in many sensory neurons [2428682].

Mean: +40

References:
  • 10617200: Regulation of lifespan by sensory perception in Caenorhabditis elegans.
  • 2428682: Mutant sensory cilia in the nematode Caenorhabditis elegans.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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