Denigma

NAM treatment

Species: Budding yeast (Taxid: 4932)
Factor: NAM
Manipulation: Diet Intervention, Drug treatment
Effect:

Treatment with NAM reduces mean and maximum replicative lifespan by 28 and 37%. NAM treatment blocks the lifespan extending effect of rapamycn [20947565].

Mean: -28
Maximum: -37

References:
  • 20947565: Rapamycin increases rDNA stability by enhancing association of Sir2 with rDNA in Saccharomyces cerevisiae.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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