Denigma

FIS1 deletion

Species: Budding yeast (Taxid: 4932)
Factor: FIS1
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion
Effect:

Deletion of FIS1 prolongs significantly mean and maximum lifespan by 13 and 29% as well as improves the fitness of old mother cells (in BY4741) [17173038].

Mean: +13
Maximum: +29

References:
  • 17173038: Reducing mitochondrial fission results in increased life span and fitness of two fungal ageing models.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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