Msra knockout

Species: House mouse (Taxid: 10090)
Factor: Msra
Manipulation: Loss-of-Function, Knockout, Mutation
Effect:

Msra homozygous knockouts exhibit a 40% shorter lifespan than wild-type or heterozygotes (C57BL/6J). Msra -/- mice have enhanced sensitivity to oxidative stress, accumulatehigher levels of protein cabronyls, and demonstrate and atypical walking pattern [11606777].

Mean: -40

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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