Denigma

mec-8 mutation

Species: Nematode (Taxid: 6239)
Factor: mec-8
Manipulation: Loss-of-Function, Knockout, Mutation
Effect:

Recessive loss of function allele in mec-8 extends lifespan [10617200]. mec-8 mutations are mechanosensory defective and have defective dye filling of sensory neurons [8625846].


References:
  • 10617200: Regulation of lifespan by sensory perception in Caenorhabditis elegans.
  • 8625846: The mec-8 gene of C. elegans encodes a protein with two RNA recognition motifs and regulates alternative splicing of unc-52 transcripts.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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