eat-18 mutation

Species: Nematode (Taxid: 6239)
Factor: eat-18
Manipulation: Loss-of-Function, Mutation
Effect:

Mutations in eat-18 extend lifespan by 15-60%. Lifespan extension is proposed to be similar to DR [9789046]. eat-1 mutants have defects in pharyngeal feeding behavior [8462849].

Mean: +15 to +60

References:
  • 9789046: The genetics of caloric restriction in Caenorhabditis elegans.
  • 8462849: The genetics of feeding in Caenorhabditis elegans.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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