Denigma

mld heterozygous mutation

Species: Fruit fly (Taxid: 7227)
Factor: mld
Manipulation: Loss-of-Function, Mutation
Effect:

Female, but not male, heterozygous mutants display a 42% increase in mean lifespan at 29 degrees Celsius. DTS-3 +/- female adults exhibit a 50% reduced ecdysone titer and reduced fertility [12610309]. Female, but not male, heterozygoutes also exhibit a temperature-dependent increase in starvation resistance.

Mean: +42

References:
  • 12610309: Steroid control of longevity in Drosophila melanogaster.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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