Denigma

DNL4 deletion

Species: Budding yeast (Taxid: 4932)
Factor: DNL4
Manipulation: Loss-of-Function, Mutation
Effect:

DNL4 deletion does not affect lifespan [10521401], although it renders cells defective for non-homologous end-joining [9242411]


References:
  • 10521401: The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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