Denigma

p53 overexpression

Species: Fruit fly (Taxid: 7227)
Factor: p53
Manipulation: Gain-of-Function, Overexpression
Effect:

Overexpression of wild-type Dmp53 during adult life has no significant effect on lifespan [16303568].


References:
  • 16303568: Neuronal expression of p53 dominant-negative proteins in adult Drosophila melanogaster extends life span.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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