iftb-1 RNAi

Species: Nematode (Taxid: 6239)
Factor: iftb-1
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

RNAi knockdown of iftb-1 at 25.5 degree Celsius continuously extends mean and maximum lifespan by 13 and 11%, while knockdown only during the adulthood extends mean and maximum lifespan by 16 and 6% [16720740]. RNA interference if iftb-1 in adulthood increases maximum lifespan by about 30% [17266679].

Mean: +13 to +16
Maximum: +6 to +30

References:
  • 16720740: daf-16 protects the nematode Caenorhabditis elegans during food deprivation.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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