Denigma

daf-10 mutation

Species: Nematode (Taxid: 6239)
Factor: daf-10
Manipulation: Loss-of-Function, Knockout, Mutation
Effect:

Loss of function mutation in daf-10 increases lifespan by 60% (in Bristol N2) [10617200]. daf-10 mutants are dauer defective, dye filling defective, octopamine deficient and have abnormal chemotaxis and osmotic avoidance. Mutants in daf-10 display abnormal sensory anatomy, especially amophidial neurons and sheath cells, and cephalic neurons. daf-10 mutant males do not mate [2428682].

Mean: +60

References:
  • 10617200: Regulation of lifespan by sensory perception in Caenorhabditis elegans.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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