Cct1 overexpression

Species: Fruit fly (Taxid: 7227)
Factor: Cct1
Manipulation: Gain-of-Function, Overexpression
Effect:

Overexpression of Cct1 from a doxycycline-inducible promoter results in a 6 - 8% increase in mean lifespan (in the PdL x rtTA; Oregon-R x rtTA strain) [12620118].

Mean: +6 to +8

References:
  • 12620118: A search for doxycycline-dependent mutations that increase Drosophila melanogaster life span identifies the VhaSFD, Sugar baby, filamin, fwd and Cctl genes.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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