Denigma

nlp-7 RNAi

Species: Nematode (Taxid: 6239)
Factor: nlp-7
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

nlp-7 RNAi reduces oxidative stress resistance and shortens lifespan of wild-type under AL. nlp-7 RNAi significantly reduces extended lifespan of eat-2 mutants, but failed to block lifespan extension of age-1 or clk-1 mutants [19783783].


References:
  • 19783783: Life-span extension by dietary restriction is mediated by NLP-7 signaling and coelomocyte endocytosis in C. elegans.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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