Denigma

mtch-1 RNAi

Species: Nematode (Taxid: 6239)
Factor: mtch-1
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

RNA interference against mtch-1 post-development extends mean lifespan by 21% [17411345]. mtch-1 RNAi in the adulthood extends the lifespan by 2.4 [New longevity regulators].

Mean: +2.4 to 21

References:
  • 17411345: Lifespan regulation by evolutionarily conserved genes essential for viability.
  • 23144747: Prediction of C. elegans Longevity Genes by Human and Worm Longevity Networks.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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