Denigma

slcf-1 mutation

Species: Nematode (Taxid: 6239)
Factor: slcf-1
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion
Effect:

slcf-1 mutation increases average lifespan by 40%. DR (by dilution of bacteria on solid medium or by bacterial deprivation) failes to extend slcf-1 mutant's long lifespan and lifespan is even reduced by lowering bacteria concentration (i.e. higher strength of DR) [21040400].

Mean: +40

References:
  • 21040400: Pyruvate imbalance mediates metabolic reprogramming and mimics lifespan extension by dietary restriction in Caenorhabditis elegans.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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