Denigma

l(3)neo18 RNAi

Species: Fruit fly (Taxid: 7227)
Factor: l(3)neo18
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

Under rich nutritional conditions lifespan of l(3)neo18 (alias CG9762) RNAi knockout animals is indistinguishable from wild-type, while upon DR, lifespan extension is diminished in males and females [19804760].


References:
  • 19804760: 4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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