Denigma

ZTA1 deletion

Species: Budding yeast (Taxid: 4932)
Factor: ZTA1
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion
Effect:

Deletion of ZTA1 increases replicative lifespan by 15% in the alpha strain and decreased by 10% in the a strain [18340043]. Although ZTA1 was identified as a potential long-lived mutant strain in a bar-code screen, deletion of ZTA1 does not significantly affect chronological lifespan under starvation/extreme DR [20657825].


References:
  • 20657825: Genome-wide screen in Saccharomyces cerevisiae identifies vacuolar protein sorting, autophagy, biosynthetic, and tRNA methylation genes involved in life span regulation.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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