Denigma

CKA2 deletion

Species: Budding yeast (Taxid: 4932)
Factor: CKA2
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion
Effect:

CKA2 deletion approximately doubles mean chronological lifespan under starvation/extreme DR in BY4741 also increases as well as as heat-shock resistance in SDC medium in the W303-1A and DBY746 genetic backgrounds [20657825].


References:
  • 20657825: Genome-wide screen in Saccharomyces cerevisiae identifies vacuolar protein sorting, autophagy, biosynthetic, and tRNA methylation genes involved in life span regulation.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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